![]() ![]() Remember that Nyquil products contain a few different ingredients. ![]() Other products that contain the same ingredients as Nyquil To avoid serotonin syndrome with MAOIs and Nyquil, you shouldn’t take Nyquil products that contain dextromethorphan within 2 weeks of an MAOI. Serious symptoms may include agitation, high fever, and fast heart rate. But in severe cases, serotonin syndrome can be life-threatening. It’s usually managed by stopping the medications that are causing it. Serotonin syndrome is usually mild, and may cause symptoms like tremor and sweating. Both dextromethorphan and MAOIs raise serotonin levels. Serotonin is a chemical that’s involved in many bodily processes. Serotonin syndrome is a rare medical condition of too much serotonin. The dextromethorphan in NyQuil can interact with MAOIs and cause serotonin syndrome. Examples include isocarboxazid ( Marplan), phenelzine ( Nardil), and selegiline ( Emsam, Eldepryl). Monoamine oxidase inhibitors (MAOIs) are medications that treat depression and Parkinson’s disease. Show them your current medication list so they can screen for possible drug interactions. So be sure to let your healthcare provider or pharmacist know if you start taking NyQuil. But keep in mind this isn’t a complete list. We’ll cover a few examples of important Nyquil interactions below. These can happen whether you take your other medications at the same time as Nyquil, or whether you take them earlier or later in the day. But drug interactions are possible with Nyquil. Should I separate any medications from NyQuil? The ingredients in NyQuil aren’t known to cause nausea, so you may be OK to take it on an empty stomach, if that’s what you prefer. This may be a better option for daytime use. It doesn’t contain an antihistamine, and it’s not known to cause drowsiness. If you need to be alert throughout the day, consider using a non-drowsy medication and reserving NyQuil for nighttime.ĭayQuil Flu and Cold is a medication that contains acetaminophen, dextromethorphan, and phenylephrine. If you’re going to take NyQuil products during the day, it’s important to avoid activities that require alertness. So although NyQuil can be taken during the day, it may make you sleepy. First-generation antihistamines are known to cause drowsiness. When is the best time of day to take NyQuil?Īll NyQuil products contain a first-generation antihistamine like doxylamine or diphenhydramine. It may be a sign that something else is going on if you have a:Ģ. If you have any of the symptoms listed below, stop taking Nyquil and reach out to your healthcare provider. It’s important to note that Nyquil isn’t meant to be used long-term. If your cold symptoms aren’t improving with the first few doses of Nyquil, talk to your healthcare provider. It’s recommended that you take it every 6 hours, since the effects only last about 6 hours.Įven if you don’t feel symptom improvement after 30 minutes, don’t take an extra dose. For example, NyQuil Cold and Flu takes about 30 minutes to start working. It may depend on what product you’re taking and what ingredients it has. Below, we’ll answer common questions about taking Nyquil and offer some tips on what you can expect. They can make sure it’s safe to take, based on your medical conditions. If you’re able to, it’s a good idea to check with your healthcare provider before taking Nyquil. But alcohol-free versions may be available. It’s a decongestant that can help clear your sinuses and relieve a stuffy nose.Īlcohol. This is the active ingredient in Sudafed PE. It’s a cough suppressant that helps relieve cough symptoms. It’s also an antihistamine.ĭextromethorphan. This is the active ingredient in Benadryl and Unisom SleepGels. Antihistamines help with runny nose and allergies.ĭiphenhydramine. This is the active ingredient in Unisom SleepTabs. ![]() It’s a pain reliever and fever reducer.ĭoxylamine. This is also the active ingredient in Tylenol. Always check the label to know exactly what’s in the specific NyQuil product you’re buying.Īctive ingredients that might be in your NyQuil product include:Īcetaminophen. And the dose of each ingredient may vary between products. Various Nyquil products may contain different ingredients. It’s a combination product that contains several ingredients. NyQuil is an OTC medication that comes in many forms. How long will it take to work? And when should you take it? What’s NyQuil? If you buy a NyQuil product, you may have questions about how to use it. It’s available over the counter (OTC) in many brand-name and generic forms. NyQuil Cold and Flu (acetaminophen/doxylamine/dextromethorphan) is one of many NyQuil products that can help relieve cold or flu symptoms. But thankfully, there are a lot of treatment options you can choose from. No one looks forward to a runny nose, headache, and coughing from the common cold or the flu. ![]()
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